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2011 Vol. 64 No. 3

Review Paper2011-05-27
The Integral System
Peter Petros
The Integral System is a total care management system based on the Integral Theory. It diagnoses and repairs damaged ligaments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .


Review Paper2011-05-12
Treatment of Mixed Urinary Incontinence
Alex Gomelsky, Roger R. Dmochowski
Mixed urinary incontinence (MUI) is a prevalent condition and imposes a significant impact on a woman's quality of life.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .


Editorial Referring10.5173/ceju.2011.03.art3
The calpain system as a potential target for pelvic muscle reinforcement.
Calpains and urinary incontinence
Robert M. Crayton, Piotr Radziszewski


Review Paper2011-07-01
The calpain system and urologic diseases. Part : Urinary incontinence.
Mariusz Blewniewski, Ewa Forma, Waldemar Różański, Magdalena Bryś
The fascial and muscular components within the pelvic floor create a support mechanism that facilitates storage and voiding of urine. Their constituents are mainly fibrillar collagens I and III responsible for maintaining tensile strength. Stretching and recoiling is enabled by the elastic fibers consisting of elastin on a scaffold of microfibrils, fibrillin-1 and-2. Calpains are intracellular Ca2+-dependent cysteine proteases found in almost all eukaryotes and some bacteria. Calpains display limited proteolytic activity at neutral pH, proteolysing substrates to transform and modulate their structures and activities, and are therefore called "modulator proteases"


Editorial Referring10.5173/ceju.2011.03.art5
New valve-mechanical model of urinary tract function: the theory of biological dual valves.
Do we need novel and innovative hypotheses in urology?
Tomasz Drewa, Georg Steinhauser


Original Basic Research And Clinical Articles2011-07-21
New Valve-Mechanical Model of Urinary Tract Function: The Theory of Biological Dual Valves
Arpad Dani, Peter Szendrö
Until now, peristalsis has been the only known method of urine transport. The main objective of this paper was to study urinary tract function - especially the upper urinary tract, the ureter - from a new mechanical point of view. The physical (physical dual valves) and biological basis (biological dual valves) of a new functional model is presented, based on previous observations and knowledge.


Editorial Referring10.5173/ceju.2011.03.art7
Is there a link between soft drinks and erectile dysfunction?
Dorota Olszewska-Słonina


Review Paper2011-05-09
Is there a link between soft drink and erectile dysfunction ?
Jan Adamowicz, Tomasz Drewa
This review focuses on the potential role of soft drinks, particularly the sugar component, in the pathogenesis of Erectile Dysfunction (ED). We analyzed hypothetical link between metabolic disorders, induced by sweetened soft drinks overconsumption, and ED. ). High caloric intake, high refined-carbohydrates and Fructose Corn Syrup (HFCS) content and less satiety are main factors responsible for metabolic disorders contributing to ED development. Regular diet mistakes, such as soft drink consumption, may lead a in human males to slow and asymptomatic progression of ED, finally resulting in full claimed manifestation of ED.


Original Basic Research And Clinical Articles2011-07-01
Salvage Open Radical Prostatectomy after Failed Radiation Therapy: a Single Center Experience
Michael A. Gorin, Murugesan Manoharan, Galaxy Shah, Ahmed Eldefrawy, Mark S. Soloway
Currently, there is no universally accepted approach for the management of radiation-recurrent prostate cancer. The aim of this report is to detail our experience performing salvage radical prostatectomy for patients who failed primary treatment of prostate cancer with radiation therapy.


Editorial Referring10.5173/ceju.2011.03.art10
Radical or simple nephrectomy in localized renal cell carcinoma: what is a choice?
Radical or simple nephrectomy for localized renal cell carcinoma - T he decision making is much more complex in 2011
Mark S. Soloway, David L.W. Pan


Editorial Referring10.5173/ceju.2011.03.art11
Radical or simple nephrectomy in localized renal cell carcinoma: what is a choice?
Radical or simple nephrectomy for localized renal cell carcinoma - The decision making is much more complex in 2011
Stanisław Wroński


Original Basic Research And Clinical Articles2011-06-21
RADICAL OR SIMPLE NEPHRECTOMY IN LOCALIZED RENAL CELL CARCINOMA: WHAT IS A CHOICE? Alexander Shulyak, Oleg Banyra. Danylo Halytsky Lviv National Medical University, Lviv, Ukraine. 2nd Lviv municipal polyclinic, Lviv, Ukraine.
Alexander Shulyak, Oleg Banyra
Renal cell carcinoma (RCC) accounts for approximately 3% of all adult malignancies. Surgery remains the only effective method of renal tumors treatment. In fact that in advanced RCC radical nephrectomy (RN) should remain a standard treatment. However, in localized RCC (LRCC) a real increase of survival rates realized by RN compare with simple nephrectomy (SN) or organ-sparing surgery is discussable. The aim of our study was to assess the impact of nephrectomy type on the prognosis of LRCC treatment.


Original Basic Research And Clinical Articles2011-07-01
Tranexamic Acid Decreases Blood Loss During Transurethral Resection Of The Prostate(TUR-P)
Şükrü Kumsar, Ayhan Dirim, Serdar Toksoz, Hasan S. Saglam, Öztug Adsan
Postoperative blood loss after prostate surgery is thought to be associated with an increase in urinary fibrinolytic activity. Tranexamic acid (TXA) is a potent inhibitor of plasminogen and urokinase activators and low molecular weight substance which is excreted unchanged in the urinary tract and can be administered both orally and intravenously. We investigated the effect of TXA on the amount of blood loss during transurethral resection of the prostate (TURP).


Original Basic Research And Clinical Articles2011-05-04
Operative shortening of the sling as a second-line treatment after the TVT failure.
Artur Gibas, Marcin Matuszewski, Jerzy Michajłowski, Kazimierz Krajka
Stress urinary incontinence (SUI) is defined as an involuntary loss of urine during physical exertion, sneezing, coughing, laughing or other activities that put pressure on the bladder. In some cases recurrent or persistent SUI after sling operations may be caused by too loose placement of the sling. In the current study, we describe our method of shortening of the sling as a second-line treatment of the TVT failure.


Editorial Referring10.5173/ceju.2011.03.art15
Detection of loss of heterozygosity in patients with urinary bladder carcinoma: neoplastic tissue vs. urine sedime nt cells.
Significance of CDKN2A gene A148T variant in patients with bladder cancer.
Toward a better understanding of bladder cancer - Genetic aspects are key
Tomasz Drewa


Original Basic Research And Clinical Articles2011-05-09
Detection of loss of heterozygosity in patients with urinary bladder carcinoma: neoplastic tissue vs. urine sediment cells
Magdalena Traczyk, Edyta Borkowska, Adam Jędrzejczyk, Michał Pietrusiński, Marek Rożniecki, Piotr Marks, Bogdan Kałużewski
Loss of heterozygosity (LOH) is frequently observed in urine bladder neoplasms. In the reported study, an attempt was undertaken to determine the loss of heterozygosity of TP53(17p13), RB1(13q1), CDKN2A/ARF(9p21) genes in DNA from neoplastic tissue, collected from patients with diagnosed urine bladder carcinoma, and to compare the results with those of LOH evaluation in DNA, isolated from urine sediment cells.


Original Basic Research And Clinical Articles2011-06-27
Significance of CDKN2A gene A48T variant in patients with bladder cancer
Edyta Borkowska, Adam Jędrzejczyk, Andrzej Kruk, Michał Pietrusiński, Magdalena Traczyk, Marek Rożniecki, Bogdan Kałużewski
A18T polymorphism of CDKN2A gene is observed in various neoplasms with the incidence rate of 3-35%, however, rather little is known either about the frequency of its occurrence or of its significance in urinary bladder carcinoma.


Original Basic Research And Clinical Articles2011-07-04
Effect of ALA-mediated photodynamic therapy in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) on bladder cancer cells
Ewelina Szliszka, Aleksandra Kawczyk-Krupka, Zenon P. Czuba, Aleksander Sieron, Wojciech Krol
Photodynamic therapy (PDT), alternative treatment modality for superficial bladder tumors is based on the interaction of photosensitizer and light. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising candidate for anticancer therapeutic due to its ability to selectively induce apoptosis in cancer cells. However, not all tumor cells are sensitive to TRAIL. TRAIL-resistant cancer cells can be sensitized to TRAIL induced apoptosis by anticancer agents.. . . . . . . . . . .


Case Report2011-05-09
Retroperitoneoscopic ureterocutaneostomy as a method of urinary diversion in case of complicated urinary fistula after radiotherapy
Marcin Słojewski, Bogdan Torbé
The case of 71-year-old woman with massive vesico-vaginal and recto-vaginal fistula after radiotherapy treated with bilateral laparoscopic ureterocutaneostomy is presented. The retroperitoneoscopic access was applied. The technical aspects of the procedure are described. The interdisciplinary character of this not so uncommon problem is underlined. In our opinion this kind of procedure may be considered as a valuable alternative for usually used methods of urine derivation.


Case Report2011-05-09
Urethral diverticulum presenting as a scrotal mass in a paraplegic male: Report of a case and review of the literature
Ozlem Tokgoz, Husnu Tokgoz, Sema Yildiz
Male urethral diverticula are rare and can be congenital or acquired. We report a case of acquired urethral diverticulum presenting as a scrotal mass in a paraplegic male. On physical examination, the scrotal mass mimicked primary intrascrotal lesion. However, on retrograde urethrography, the correct diagnosis was made. The patient had a small incontinent spastic bladder with a history of prolonged catheterization. Eventually, the urethral diverticulum was excised including the affected segment of bulbous urethra


Case Report2011-04-19
Large tunica albuginea cyst simulating a large hydrocoele with a unique ultrasound feature.
Sani Aminu, Omar Jundi, Heshan Panditaratne
A 58 years old man presented with a large left scrotal swelling suspected

to be a large hydrocoele both clinically and on initial ultrasound. However

at operation a large tunica albuginea cyst was found arising from the mid

anterior wall of the left testis. It was dissected, excised and edges

under run. Further review of the ultrasound scan revealed a unique feature

of large tunica albuginea cyst simulating a hydrocoele.


Scientific integrity also concerns editors and publishers

Recently, there have been many dishonest propositions from scientific publishing houses and publishers. Authors receive offers to publish articles in journals of questionable reputability and often an unfairly created image which portrays a resemblance of a journal with high standards possessing an Impact Factor, generated by Clarivate Analytics (previously Thomson Reuters).

Many trademarks imitating the "original" Impact Factor have appeared. These trademarks entice authors to publish articles in journals which do not appear in the Science Citation Index Expanded database, managed by Clarivate Analytics. These journals of course have their own unique impact factors, but they are not indexed by Clarivate Analytics. Authors publish their articles in these journals only to later find out that they will not be indexed in the Science Citation Index Expanded database. Often, these articles cannot be then withdrawn because after an article is assigned a DOI number, it cannot be published in another journal as this would be considered plagiarism. Subsequently, these journals may demand up to a few thousand dollars from authors in order to withdraw their articles.

Why am I writing about this? I am writing about this because I think that editors and publishers must be honest and present credible offers to authors. In my opinion, impact factors that are not the result of parameters calculated by Clarivate Analytics should not be used, even if they are trademarks. In scientific research, the concept of an "Impact Factor" has existed for too long for it to be used by other institutions, even if it is calculated fairly and called an "unofficial impact factor". This is simply a case of scientific integrity.

The SCOPUS database has come up with a very good solution to this problem by naming their impact factor "CiteScore". This is a fair approach to authors by publishers.

As editors and publishers, we must also have an honest approach to scientific research.

Dear authors, please look out for journals which advertise various new impact factors. Before you submit your articles to a journal, make sure to check first in which database it is indexed.

With kind regards,
Tomasz Drewa


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The Editorial Office would like to inform all interested parties that in Central European Journal of Urology an article entitled "Efficacy of holmium laser urethrotomy and intralesional injection of Santosh PGI tetra-inject (Triamcinolone, Mitomycin C, Hyaluronidase and N-acetyl cysteine) on the outcome of urethral strictures" [Kumar S, Kishore L, Sharma AP, Garg N, Singh SK. Cent European J Urol. 2015; 68: 462-465] was published which is very similar to the article entitled "Efficacy of Optical Internal Urethrotomy and Intralesional Injection of Vatsala-Santosh PGI Tri-Inject (Triamcinolone, Mitomycin C, and Hyaluronidase) in the Treatment of Anterior Urethral Stricture" published in Advances in Urology [Kumar S, Garg N, Singh SK, Mandal AK. Adv Urol. 2014; 2014: 192710. doi: 10.1155/2014/192710. Epub 2014 Oct 1].

The authors of these articles did not inform the CEJU Editorial Office about the prior publication of an article with a similar subject matter nor did they refer to it in their References section.

The Editorial Office regrets the existing situation.